The final battle with the Witness begins.
The reason why the Witness wants to destroy time and all reality is revealed.
Former friends, now enemies, race to find the Witness in 1904, who, at last, reveals his face.
One team, two agendas and a single event that changes the course of the mission, and pits friend against friend.
The origin of the Army of the 12 Monkeys is revealed, with an influence from Christopher Lloyd.
To track the Witness, the gang must travel to the most outrageous era yet- the 1980s.
Cole faces the unthinkable to save the woman he loves; an escape from the time traveling city of Titan.
An old enemy unveils a dangerous new scheme which could shatter bonds and unravel reality.
Cole travels to 1922 and faces new enemies; the origins of the Witness' world-ending plan are revealed.
The birth of the Witness and the beginning of the end of the world.
Cole and Railly adjust to the past, but a mysterious women with apocalyptic visions gets them to do the unthinkable to save the world.
Cole and Railly attempt to stop the final paradox; Ramse, Jennifer and Deacon struggle to survive the apocalypse in an effort to find the Witness.
As the temporal facility gets closer to destruction, Cole goes to 1957 to save humanity while everyone else looks for Titan, the stronghold of the Witness.
Ramse and Railly try to find a German doctor who knows the location of The Witness during an unsanctioned mission in 1961.
Jennifer Goines forms The Hyenas to take on the 12 Monkeys' organization, and with the help of Cole, they discover a plan to acquire the virus.
Jones realizes that humanity's true enemy is time-travel itself, and decides to send Railly back to 2020 to undo everything; Cole and Railly discover an anomaly during their quest.
Cole faces the Witness as Cassie's hallucinations evolve; deadly visitors from the past arrive when the time machine malfunctions and begins tearing apart time and space.
Cole and Ramse travel to 1970s New York City to prevent the Twelve from murdering a Vietnam veteran with a connection to the Witness.
In the present, Cassie and Jennifer Goines run from the 12 Monkeys; in 2044, Cole and Ramse face off against Deacon.
Jones turns to Ramse for help getting Cole and Cassie back from 1944; Jones visits old Jennifer Goines to explore the true nature of time.
Despite the growing tension between them, Cole and Cassie time travel to New York during World War II to track down a dangerous member of the Twelve.
Cole gets stranded in 2016 after an attempt to destroy the virus changes the future; Jones and Railly deal with the consequences of the changed timeline.
Cole and Ramse repair their broken friendship while on the run; Railly and Jones navigate an uncertain future in 2043.
Cole and Cassandra try for a final confrontation with the Witness, while Jones faces a new threat to the mission.
Cassandra must find the only person that can save Cole from dying due to the taxing effects time travel has on his body.
Cole makes a last-ditch effort to stop the Army of the 12 Monkeys, splintering to 1987 Tokyo; another level of the narrative is revealed.
Forces come to a head when Ramse takes measures to protect his newfound family, leaving Cole to deal with the fallout.
Cole finds himself at the height of the plague in 2017; Jones faces an impossible choice to replace the Core.
As the Core begins to fade, Jones must convince her former colleagues that the mission is worthwhile in order to get Cole back from the past.
Cole, Dr. Railly and Aaron strive to prevent the virus from being deployed as a bio-weapon in Chechnya.
When the tragic events of the Night Room create an alternate reality in 2043, Cole risks his future to save Dr. Railly.
Cole and Dr. Railly discover the Night Room, which houses the virus that will one day destroy the world.
A dangerous band of marauders that are hunting for Cole and Ramse threatens the mission to save the past.
Cole is led to Haiti in 2014, where a dangerous outbreak proved to be a devastating moment in Dr. Railly's life.
A patient in a mental institution may hold the key to the plague that destroys the world; Dr. Railly risks her life to help Cole, despite the risk to history.
After a virus wipes out humanity, a man is sent back in time to stop the plague from ever happening by finding a virologist who knows the outbreak's source.