Alex tries to distract herself from her grief; Charlie and Shahir try to track down Alex's brother.
The doctors rally together to try to save an unknown man who was struck by a subway train; Charlie realizes who the John Doe is.
Charlie and Manny treat a couple; Maggie evaluates the interns; Billy asks Maggie to be his mentor; Dawn tries to get her Chief of Surgery position back.
Alex and Maggie deal with a tough lawyer after surgical complications with their cancer study patient; with the E.R. now an urgent care facility, Zach and his team aren't equipped to handle an accident victim.
Alex's alarm at home goes off; Alex and Maggie ask Charlie for his opinion on a patient's treatment; Zach is persuaded by a patient while transitioning the ER to an urgent care facility.
Alex tracks down the father of a patient who needs a liver transplant; the new CEO of Hope Zion is at odds with Dawn; Zach faces trials in the E.R.
Charlie tries to save the arm of a man thrown from a horse; Alex joins Manny off-site to help a runaway; a rival from Dev's past arrives at Hope Zion.
Alex makes a promise to a young girl on her birthday; Maggie organizes a surprise party for Alex; Cassie is forced to confront her fear of infectious diseases.
Alex and Charlie are confused about their relationship; Alex and Maggie disagree about a car crash survivor; Dana is forced to treat an injured motorcyclist; Zach bothers Maggie about dating.
While searching for Charlie, Alex finds a caterer who was caught in the crossfire; Grace's mother asks for a priest; Dana consults with Cassie about a male stripper.
Alex and Shahir struggle to save Charlie's life.
Kristine suffers a stroke, which impacts her memory; Alex and Charlie team up to bring her peace; Alex and Shahir struggle to save Charlie's life.
Kristine suffers a stroke, which impacts her memory; Alex and Charlie team up to bring her peace.
Alex and Cassie try to free a young woman from her abusive partner; a patient's pacemaker malfunctions.
Charlie decides to go a day without using his special abilities; Alex organizes a trip to Dana's cabin; Zach takes control of a life and death situation involving Dawn's college roommate.
Alex and Jeremy try to solve a child's mystery illness; Charlie treats an actor; Maggie reaps the rewards of compassionate medicine.
Kristine shows up at the hospital with baby Luke's blanket.
Faced with a chef who refuses treatment, Alex is forced to confront how she feels about Dana's methods.
During an ice storm on Christmas Eve, Alex and Dawn fight to keep a woman alive long enough for her family to say goodbye.
Alex discovers that she unknowingly helped the bomber at the expense of a friend.
Casualties of a bomb at a local charity run arrive at Hope Zion Hospital.
When a trapeze artists dies, a line of patients in need of his organs cause complications.
Alex tries to convince Shahir to use an aggressive treatment on a brain tumor patient.
Alex must decide whether or not to use the info Charlie got from a patient's spirit.
When a young motocross rider is diagnosed with Leukemia, Alex investigates his family secrets.
The man responsible for Alex's brother's drug problem is admitted to the hospital.
Alex struggles with being a mom, a surgeon and now mentoring a junior resident.
Alex puts her reputation on the line when she questions a senior surgeon's methods.
Dr. Alex Reid returns from maternity leave and treats a mother who was in a car accident.
At an off-site army base, Joel and Zach get in a precarious situation; a hypothermia victim fights for the life; Alex, Maggie and Rian write their Surgical Boards.
Alex and Dana try to save a single mother's life; a hockey player's mobility is at stake; Charlie gets advice on winning back Alex; Sydney comes clean.
Alex and Charlie try to save the life of a man on the run; a spirit won't leave Alex alone; Maggie and Zach try to help a couple; Joel and Shahir help a bride walk down the aisle.
Alex asks for help in diagnosing a teacher with a mysterious illness; Charlie must explain his actions; Dawn must make a big decision.
Alex and Maggie perform an intricate procedure; Joel thinks his dad is hiding something; Charlie suspects foul-play when he sees a boy and his grandmother.
Alex encounters a trapped teenager during a hike in the woods; a woman refuses to see anyone but Joel; an exotic dancer comes to the ER.
Two patients need the same heart; a patient has never-before-seen orthopaedic hardware; Dr. Maggie Lin feels the pressure of the upcoming boards.
Charlie tries to treat two female MMA fighters; a fight between Dana and Molly ends up in the hospital; Dawn must save a woman's heart.
Celebrated neurosurgeon Thor MacLeod gives Alex an offer; Charlie deals with a fatigued spirit; Joel ends up in a fight at the clinic.
Alex and Joel must perform a marathon surgery; Charlie's day off is full of surprises; a hospital frequenter tests Dana, Zach and James.
Alex and Charlie perform a double surgery on a teenage girl; Joel works at the clinic; Maggie must pull through when she is reunited with the Zarb family.
Shahir and Alex attempt a radical surgery on an Alzheimer's patient; Tom discovers his mentor is keeping a secret; Charlie is torn between Dawn's wishes and the final requests of a dead con-man.
Alex, Maggie and Joel face a medical mystery; Charlie meets a patient with an usual link; an unexpected visitor has Zach questioning his abilities as a dad.
When a son wants to be involved in his mother's surgery following a car accident, her spirit tells Charlie how she feels; Maggie and a new resident get involved in a hazardous situation.
Alex meets her "buddy colleague" upon returning to work; Joel gets involved in a deadly situation; an unlikely ally helps Gavin.
A crisis at the hospital jogs Alex's memory; a building collapse forces Charlie and Joel to work together; the doctors try to give Maggie some advice.
Alex's spirit goes on a journey with Charlie; Joel be-friends a drug addict; the new OB/GYN throws Maggie off her game.
Dr. Alex Reid has a profound experience and Charlie and Dawn try to save her life; Joel's duty is tested by a suicidal patient; Maggie's decision changes her relationship with Gavin.
Alex is diagnosed with an irregular heartbeat but must care for the Great Randall; Charlie deals with the aftermath of the fight; one of the staff is attacked.
An elderly patient believes she's living in a different time; Charlie and Joel get competitive; Maggie is forced to take the reins during a surgery.
Alex races to find an organ replacement; Joel helps a couple; Charlie is pushed to his breaking point.
A couple is attacked by a bear, but Alex and Charlie think there's more to the story; a Buddhist tries to teach Joel a lesson.
Alex witnesses an accident involving a John Doe; Charlie and Gavin have a spiritual therapy session.
Alex is tricked into going on a blind date and has to rush him to the ER; Charlie helps a soldier; a patient with a contagious illness puts Maggie at risk.
Alex performs surgery on one of the hospital's own doctors; a routine checkup turns deadly; a medical conspiracy extends far beyond Hope Zion.
Alex performs a risky surgery to save a boy's life; Joel struggles with his new career and Charlie struggles with the spirit of a patient.
Joel and Charlie tend to Alex's brother; a pregnant patient must have a tumour removed.
Alex puts a surgery on hold when she discovers the patient's medical history; a patient is convinced she'll die at midnight; Joel helps Sonja with a patient.
Alex and Joel get stranded with an injured couple; Charlie tries to save his friend's leg; Gavin tries to help Shahir with his bedside manner.
The hospital gets an influx of patients during a heat wave and the team must deal with a power outage.
Alex investigates the death of a firefighter; Charlie deals with a nun; Joel decides whether or not to come through for Sonja.
A young prisoner is brought to the hospital; Joel tries to convince Dr. Dana Kinney to operate on a disfigured refugee; a familiar spirit appears in the morgue.
Alex, Charlie and Joel operate on a malpractice lawyer; Zach deals with an unwanted patient; a patient returns with some insight.
Struggling to get her life back to normal, Alex finds inspiration from an immigrant doctor.
Alex tries to stick up for herself against Dawn to perform a heart procedure while Joel figures out a girl's disease and Charlie attempts to bring back a comatose patient.
Alex and Charlie get caught in a shooting on their way back to Hope Zion and tend to the victims.
A major turn of events could permanently change Alex's life; Joel must work quickly to save a young patient from a flesh-eating disease that is rapidly accelerating.
Shahir and Alex plan a last-resort procedure for Charlie, but Charlie must come to terms with his past before he can wake up; a female jockey undergoes risky surgery; Gavin crosses the line with a patient.
A passenger's illness forces a plane to land; when Alex performs emergency surgery on the patient, she realizes a deadly and contagious virus may have been brought into the hospital.
Kinney tries to help Joel clear his head by taking him on an assignment in her hometown; Alex treats a fitness buff with a rare condition.
A patient's symptoms lead to a discovery about Charlie's coma; Joel's injury keeps him from operating; Gavin and Maggie face the aftermath of their kiss.
Alex and Dawn argue over who should be Charlie's legal decision maker; Charlie doesn't want to talk to a deceased prisoner who provided a heart for Alex's patient.
Alex's patient falls into a coma during a routine surgical procedure and encounters Charlie in the spirit world; Joel treats a patient who does his own body modifications.
When a hypnotist is called into the hospital to help with a patient who can't remember his identity, the man uses his psychic ability to connect Charlie and Alex.
A double hand reattachment gives Alex a chance to prove that she is still capable of being chief surgical resident; Maggie thinks a homeless man received the wrong diagnosis.
An exhausted Alex treats a hockey player while working the nightshift in the ER; Charlie meets a punk who is facing a difficult fight.
Cheered by Charlie's movement, Alex treats a patient who has already undergone many surgeries; Charlie helps a dead man who has unfinished business with his gravely injured brother.
Alex Reid treats a boy with mysterious symptoms while dealing with the arrival of Charlie's ex-wife; Joel and Maggie try to help a patient who is refusing treatment because of religious beliefs.
When Charlie Harris, Hope Zion Hospital's chief of surgery, falls into a coma, he ends up wandering the hospital in spirit form.
Alex precisa defender-se de Dawn para realizar um procedimento cardíaco; Joel tenta compreender a doença de uma menina; Charlie tenta acordar paciente de um coma.
Alex e Shahir decidem fazer a última tentativa de estimular o cérebro de Charlie através de uma cirurgia arriscada. Sem saber, eles o obrigam a reviver antigos traumas onde ele pode tomar um caminho sem volta.
Joel recebe uma proposta para ficar no hospital, mas que pode prejudicar uma colega da equipe. Alex ainda está se adaptando às mudanças após a cirurgia de Charlie e ele descobre que sua vida nunca mais será a mesma.
O cérebro de Charlie está sendo estimulado por um aparelho e ele acaba tendo que enfrentar fantasmas do seu passado. Enquanto isso, o hospital é isolado em quarentena, deixando a equipe com os nervos à flor da pele.
Charlie recebe a visita de uma terapeuta da TV que o faz ver por que não consegue acordar. A dra. Kinney leva Joel numa viagem para esquecer o incidente com o policial, mas um acidente o obriga a enfrentar o trauma.
Bea, diagnosticada quatro anos antes com um linfoma, tem uma reviravolta no seu caso que leva a novas descobertas sobre Charlie; Alex contrata outra advogada; Joel tem que ficar fora da sala de cirurgia; Gavin e Maggie se reencontram depois do beijo.
Alex e Dawn disputam na Justiça o direito de decidir sobre a vida de Charlie; Charlie conversa com o prisioneiro morto que doaria o coração para um paciente operado pelas equipes das duas médicas; o Dr. Goran tenta ajudar um policial suicida.
Uma paciente da Dra. Reid sofre uma complicação durante uma cirurgia simples e entra em coma. A médica consegue trazê-la de volta e renova suas esperanças quanto a Charlie, mas o tempo dos dois pode estar acabando.
O emprego de Alex está em perigo e sua atuação numa cirurgia complicada é a oportunidade ideal para ela se afirmar. Charlie conhece alguém que está em coma há 27 anos e ganha uma nova perspectiva sobre sua situação.
A dra. Reid tem a difícil tarefa de convencer um jogador de hóquei a parar de jogar para evitar o pior. O quadro de Charlie piora, mas ele ganha a companhia de um rapaz em coma com quem pode aprender a acordar.
Charlie conhece Isaac, um homem que ficou com assuntos mal resolvidos com seu irmão, que também está internado. Sua companhia faz com que ele entenda um pouco melhor a situação dos mortos no hospital.
A médica Alex Reid luta para manter vivo o noivo Charlie, que entrou em coma após um acidente de trânsito.